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KMID : 0374020030260020077
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Ewha Medical Journal
2003 Volume.26 No. 2 p.77 ~ p.83
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A Prospective Randomized Study Comparing Open Versus Laparoscopy-Assisted Distal Gastrectomy in Early Gastric Cancer
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Lee Jae-Hyeok
Lee Joo-Ho
Seoh Ju-Young
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Abstract
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Methods : Forty-seven patients, endoscopically diagnosed as EGC on antrum and lower body, were included during the period from November 2001 to August 2003. Using a random number table, 23 patients were assigned to open group(group O) and 24 patients to LADG group(group L). Radical distal subtota 1gastrectomy with gastroduodenostomy was performed in all patients. The clinicopathologic findings, postoperative recovery, and morbidity were compared between two groups.
Results : Age, sex, body weight, associated disease, history of previous abdominal surgery, location of lesion, size, gross type of EGC, and histologic differentiation were similar in both groups. On permanent pathologic examination, all cases of group O were diagnosed as EGC and in the group L, 21 cases were EGC, 3 cases were advanced cancer. The mean operation time was significantly shorter in the group L, but estimated blood loss and transfusion amount were similar in both groups. The mean postoperative days of first flatus, starting day of diet, postoperative hospital stay were shorter and deration of analgesic administered were lower in group O, but they did not reach statistical significance. The mean numbers of harvested lymph nodes were 38.1 in the group O and 31.8 in the group L, which was not statistically significant(p=0.098). Postoperative pulmonary complication based on chest X-ray occurred more frequently in the group O (p=0.043). There is no recurrence of disease in both groups in follow-ups.
Conclusion : LADG has advantage in terms of less phlmonary complications while main-taining the curatility. This is the preliminary result of prospective randomized study and the long-term results should be followed.
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KEYWORD
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Laparoscopy-assisted distal gastrectomy, EGC, Prospective randomized trial
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